Items:
	Sad Onion +0.7 Tears Stat.
	The Inner Eye Tears now shoot three at a time (Triple shot). Tears down significantly: (delay = delay * 2.1 + 3). This essentially lowers your tear rate by about 2 tears per second.
	Spoon Bender Gives the player homing shots. This item is a 'Special' item.
	Max's Head +0.5 Damage Stat. Gives shots a significant knockback effect. Adds a x1.5 damage multiplier. This item is a 'Special' item.
	My Reflection Gives tears a boomerang effect. Synergises well with the Lump of Coal item, due to the fact that items stay airborne longer.
	Number One Greatly increase rate of fire and greatly decrease tear range. +1.5 Tears Stat. -13 Range Stat.
	Blood of The Martyr +1 Damage Stat. Adds a x1.5 damage multiplier ONLY if the player also has The Devil Card/Book of Belial effect. Can appear in the Angel Room item pool.
	Brother Bobby A familiar which follows the player and shoots tears with 3.5 damage. An item commonly found in the Devil Room item pool.
	Skatole All fly enemies are no longer aggressive towards the player. 1/13 chance to see this item appear from the shell game, with a further 1/3 chance to win it (1/3 chance becomes 1/2 with the Lucky Foot).
	Halo of Flies Gives the player two orbital flies which will circle the player, block incoming shots and damage any fly-type enemies on contact.
	1UP Gives the player an extra life.. Item found in the Secret Room item pool.
	Magic Mushroom +1 Health Up. +0.3 Damage Stat. Adds a x1.5 damage multiplier. +7.75 Range Up (Base range = 23). Full heal. Does not increase the tears stat.
	The Virus Deals 30 poison damage per tick on contact with enemies. -10% Player Movement Speed Down. 25% chance to drop from the Lust mini boss.
	Roid Rage +60% Player Movement Speed Up. This item is falsely labelled as range up.
	<3 +1 Health Up.. Full Heal. 25% chance to drop from the Gluttony mini boss.
	Raw Liver +2 Health Up. Full Heal. This item is only found in the Secret Room item pool.
	Skeleton Key +99 Keys.
	A Dollar +99 Coins. Can only drop when breaking Slot Machines.
	Boom! +10 Bombs.
	Transcendence Gives the player the ability to fly. Has a 2/3 chance to be in the Secret Room item pool for each game. UNLOCK: Unlock this item by defeating Mom's Heart for a second time.
	The Compass Shows all icons on the map (Treasure room, shop, boss room etc.) Does not show the layout of the map itself. The map icons do not show if the current floor has the 'Curse of Darkness' effect.
	Lunch +1 Health Up.
	Dinner +1 Health Up.
	Dessert +1 Health Up.
	Breakfast +1 Health Up.
	Rotten Meat +1 Health Up.
	Wooden Spoon +30% Player Movement Speed Up.
	The Belt +30% Player Movement Speed Up.
	Mom's Underwear +7.75 Range Up (Base range = 23).
	Mom's Heels +7.75 Range Up (Base range = 23).
	Mom's Lipstick +7.75 Range Up (Base range = 23).
	Wire Coat Hanger +0.7 Tears Rate Modifier.
	The Bible Gives the player angel wings and the ability to fly for the current room.. Instantly kills Mom's Foot and Mom's Heart. Instantly kills the player if used on the Satan, Isaac or ??? boss fights. Can appear in the Angel Room item pool. Recharge Time: 6 Rooms.
	The Book of Belial +2 Damage Stat. Adds a x1.5 damage multiplier ONLY if the player also has 'Blood of the Martyr'. Gives a 25% higher chance to spawn a Devil Room while holding this item. UNLOCK: Unlock this item by using defeating the Mom's Heart boss fight for the first time. Recharge Time: 3 Rooms.
	The Necronomicon Deals 40 damage to all enemies in current the room. An item sometimes found in the Devil Room item pool. UNLOCK: Unlock this item by using enough Death Tarot Cards. Recharge Time: 6 Rooms.
	The Poop Drops a poop on the floor. The poop can be used to block enemies and has a chance to drop pickups (i.e. coins, hearts), just like normal poops can. The ??? character starts with this item. UNLOCK: Unlock this item by defeating the Mom's Heart boss fight ten times. Recharge Time: 1 Rooms.
	Mr. Boom Drops a large bomb below the player which does 110 damage. 25% chance to drop from the Wrath mini boss. Recharge Time: 2 Rooms.
	Tammy's Head GFires 10 tears in a circle around the player. Can be found in Golden Chests. Recharge Time: 1 Rooms.
	Mom's Bra Freezes all enemies in the room for 5 seconds. Recharge Time: 3 Rooms.
	Kamikaze Causes an explosion near the player which damages all enemies in close proximity for 40 damage per use. The explosion makes the player take 1 heart of damage. There is a known glitch with this item where if the player hugs a wall and uses it, they won't take damage but the explosion will still occur. Recharge Time: Instant.
	Mom's Pad Causes all enemies to flee from the player for a short time. Recharge Time: 3 Rooms.
	Bob's Rotten Head A poison bomb which can be thrown to cause 53.5 poison damage to enemies and leaves a poison effect on the enemy, doing 3.5 damage per tick. Damage done from this item is affected by items which increase your damage stat. 25% chance to drop from the Sloth mini boss. Recharge Time: 3 Rooms.
	Pills Here! Just a place holder.
	Teleport! Teleports the player to a random room. This item cannot teleport you to the I AM ERROR room. Recharge Time: 2 Rooms.
	Yum Heart Heals the player for one whole red heart. Maggy starts with this item. 14.3% chance to drop from the Super Lust mini boss. UNLOCK: Unlock this item by having 7 heart containers in a single playthrough. Recharge Time: 4 Rooms.
	Lucky Foot All pills will now have positive or neutral effects. Increases chance to win shell game (50% up from 33%). Increased chance to win at a slot machine. Always get a drop from the fortune machine. +10% chance to get a drop after clearing a room. UNLOCK: Unlock this item by collecting 55 pennies in one playthrough.
	Doctor's Remote A one time use of Epic Fetus. A target is placed on the floor which can be controlled with the arrow keys or mouse. After several seconds a missile hits the target and does 80 damage to anything within range. You start with this item in the 'The Doctor's Revenge' challenge. Recharge Time: 3 Rooms.
	Cupid's Arrow Gives the player piercing shots which will travel through all enemies. Shots will not travel through rocks with this item.
	Shoop Da Whoop One time use of a Brimstone style laser, which can be shot in any direction causing 22 daamge per tick, for up to a maximum of 4 ticks per laser. The Brimstone glitch does not work with this item. 25% chance to drop from the Envy mini boss. Recharge Time: 3 Rooms.
	Steven +1 Damage Stat. 1/6 chance to drop from the 'Steven' boss fight or 100% chance if you already have the 'Little Steve' item. Killing the smaller part of Steven first does not increase the chances for this item to drop. Can also appear in golden chests.
	Pentagram +1 Damage Stat. Adds a 20% chance for a Devil Deal Room to spawn. Adds an extra 10% chance for a Devil Deal Room to spawn if you somehow picked up a second one.
	Dr. Fetus Player's shots are now Bombs instead of tears which do 60.5 damage as a base and increase slightly with upgrades in the damage stat. Picking up the Mr. Mega item will turn your bombs into super troll bombs. Picking up the Bobby Bomb item will cause Dr. Fetus bombs to move towards enemies. Augments the item pool with 'Bobby - Bomb' and 'Mr. Mega', adding six of each item. UNLOCK: Unlock this item by defeating Mom's Heart for a fifth time.
	Magneto Pick-ups on the floor move towards the player.
	Treasure Map Reveals the entire map for every floor including the secret room. Does not show icons for any other rooms. The map does not show if the current floor has the 'Curse of Darkness' effect. Item found in the Shop Room item pool.
	Mom's Eye Player now also shoots tears out the back of their head. This item is falsely labelled as a tear stat up. The rate of tears coming from the front of Isaac does not increase as a result of picking up this item.
	Lemon Mishap Creates a pool of yellow 'lemonade' on the floor for 5 seconds which damages any enemies which come in contact with it rapidly for 8 damage per tick. Recharge Time: 2 Rooms.
	Distant Admiration Gives the player an attack fly which orbits Isaac at a further radius than normal orbitals and deals damage to any enemies which come in contact with it. The Distant Admiration fly does 5 damage per tick and does not scale with damage stat upgrades.
	Book of Shadows Gives the player an invulnerability effect for 300 frames (10 seconds) on use. This item can allow the player to take free deals with the devil which are on sale for three Soul hearts, if the invulnerability effect is used. Recharge Time: 3 Rooms.
	Wiggle Worm Tears now move in a wave fashion across the screen. +0.4 Tears Stat.
	The Ladder Allows the player to walk over gaps with a width of one tile. Found in the Shop Room item pool.
	Tarrot Card Just a placeholder.
	Charm of the Vampire Heals the player for 1/2 a heart after every 13 enemies killed.
	The Battery Gives the player one extra charge of their spacebar item after every 15 seconds spent in a hostile room (where the doors are shut) up to a total of three charges. Using a spacebar item will reset the charge counter, meaning an extra three charges can be achieved per room (A total of six). Found in the Shop Room item pool.
	Steam Sale Lowers the price of all items in the shop by 50%, rounded down to the nearest whole number. The item becomes useless after The Depths/Necropolis 2, due to the fact that there are no shops after this point. 25% chance to drop from the Greed mini boss.
	Anarchist's Cookbook Spawns six troll bombs at random locations around the room, which do 40 damage and will damage the player if in range of an explosion. 25% chance to drop from the Pride mini boss. Recharge Time: 3 Rooms.
	The Hourglass Slows all enemies and their projectiles in the current room. Can cause 'The Fallen' boss to split into four parts if used when the boss hits 50%. Recharge Time: 2 Rooms.
	Sister Maggy A familiar which follows the player and shoots red tears. An item commonly found in the Devil Room item pool. Sister Maggy's tears do 5 damage each and do not scale with damage stat upgrades.
	Technology The player's tears are now a laser shot with unlimited range, which only fire at right angles. Shots travel through enemies but not rocks in the environment. The Lump of Coal item simply gives +2 static damage for Technology. This item has a number of interesting synergies. Having either Ipecac, The Inner Eye, Mutant Spider or Polyphemus will increase damage by a factor of three.
	Chocolate Milk The player can now charge shots by holding down the arrow key and shots will therefore no longer automatically fire. It will now be necessary to rapidly press buttons to fire tears at the highest possible rate. A fully charged shot is equivalent to +7.8 damage.
	Growth Hormones +1 Damage Stat. +40% Player Movement Speed Up.
	Mini Mushroom +30% Player Movement Speed Up. +3.25 Range Up (Base range = 23). Shrinks the player sprite size, but not the hitbox.
	Rosary Gives the player three soul hearts. Augments the shop item pool, adding 7 instances of 'The Bible' item. Picking up this item will show a message saying "Faith Up" in the bottom corner. Faith up is NOT an actual stat within the game and does not increase your chance of a God Room.
	Cube of Meat This item drops every time after defeating Famine, Pestilence, War or Death. A single cube of meat will give the player an orbital which block shots and damage anything it comes into contact with for 7 damage per tick. Picking up a second cube of meat turns it into a floating meat head which shoots red tears for 5 damage, does 7 damage on contact and blocks incoming shots. A third cube of meat turns the head into a small meat boy who walks around and damages enemies for base damage (3.5) but no longer shoots projectiles. A fourth and final cube of meat increases the meat boy's size and damage (5.5 damage). Any further cubes of meat obtained will restart the process starting with a new orbital cube.
	A Quarter +25 Coins. 14.3% chance to drop from the Super Greed mini boss. UNLOCK: Unlock this item by defeating Mom's Heart for a fourth time.
	PhD All pills now have a positive or neutral effect. Has a 1/150 chance to identify a pill every frame (30 times per second). Causes the blood donation machine to drop an extra coin. PhD also removes the chance for any unidentified pills to become telepills. Pills which are already identified as telepills will not be affected. Heals two hearts of health.
	X-Ray Vision Reveals the entrance to both the Secret room and the super-secret room. This item also automatically opens the hole, removing the need for bombs to enter.
	My Little Unicorn Gives the player temporary invincibility and damages enemies upon contact for 40 damage each tick. Recharge Time: 6 Rooms.
	Book of Revelations Adds one Soul heart upon use. Increases the chance for a Devil Deal Room to spawn by 35% while held. If you use the Book of Revelations and you are on a non-XL floor in the Womb or before, you will get one of the four horsemen as your boss. UNLOCK: Unlock this item by defeating any of the horsemen boss fights. Recharge Time: 6 Rooms.
	The Mark +1 Damage Stat. +20% Player Movement Speed Up. +1 Soul heart. An item commonly found in the Devil Room item pool.
	The Pact +0.5 Damage Stat. +0.7 Tears Stat. +2 Soul hearts. An item commonly found in the Devil Room item pool.
	Dead Cat Health is set to 1 and you gain an extra 8 lives. You can increase your heart containers as normal, however each time you die it will be reset to 1 again. This is one of the items which counts towards achieving Guppy state. Each death still adds to the death counter on the stats page in game. 1/50 chance to get this item from a Red Chest. 14.3% chance to drop from the Super Pride mini boss. An item commonly found in the Devil Room item pool.
	Lord of the Pit Gives the player the ability to fly over all obstacles +30% Player Movement Speed Up.
	The Nail Adds one soul heart upon use and allows the player to break rocks by walking over them. +0.7 Damage Modifier when activated. -18% Player movement speed down when activated. Deals 40 damage on contact with enemies, in exactly the same way both the Unicorn Horn and the Pony damage on contact effects work. An item commonly found in the Devil Room item pool. UNLOCK: Unlock this item by defeating Mom's Heart three times. Recharge Time: 6 Rooms.
	We Need To Go Deeper Spawns a trapdoor at the player's feet which allows them to travel to the next floor. Recharge Time: 6 Rooms.
	Deck of Cards Gives the player a random Tarot card when activated. Recharge Time: 6 Rooms.
	Monstro's Tooth Upon activation spawns a friendly Monstro who jumps on a random enemy and does damage 120 to it. Cannot be used in the Monstro boss fights. Cannot be used if there are no enemies in the room. UNLOCK: Unlock this item by beating every regular boss in the Basement. Recharge Time: 3 Rooms.
	Loki's Horns Normal shots now also give the player a random chance for shots to fire in all four directions (+ shape). Does not give a fire rate upgrade for normal tears. UNLOCK: Unlock this item by defeating every boss in the Depths.
	Lil' Chubby Adds a follower who charges forward every ~4 seconds in the same direction as the player's shots. Lil' Chubby deals 3.5 damage in rapid succession, resulting in a significant amount of damage. UNLOCK: Unlock this item by beating every regular boss in the Caves.
	Spider's Bite Isaac's tears now have a chance of slowing enemies and their shots for a few seconds. Item found in the Secret Room item pool. UNLOCK: Unlock this item by completing the Basement.
	The Small Rock +1 Damage Stat. +0.2 Tears Stat. -20% Player Movement Speed Down. UNLOCK: Unlock this item by destroying enough tinted rocks.
	Spelunker Hat Reveals the location of both the Secret Room and the super-secret Room. Upon entering a room adjacent to one of the Secret Rooms, the discovery sound effect will play.. Bombs are still needed to enter, unlike the x-ray vision item. UNLOCK: Unlock this item by completing the Caves.
	Super Bandage +1 Health Up. +2 Soul hearts. UNLOCK: Unlock this item by defeating the Famine, Pestilence, War and Death boss fights and defeating a total of 4 horsemen in a single playthrough (not including Conquest).
	The Gamekid The player turns into Pacman, which makes them invincible and does 40 damage on contact with enemies. Everytime you 'eat' an enemy you regain some health. Enemies will also flee from the player for the duration of the effect. UNLOCK: Unlock this item by visiting enough arcade rooms. Recharge Time: 6 Rooms.
	Sack of Pennies A coin bag follows the player and drops a coin every 2 rooms. Usually a penny, seldom a nickel. UNLOCK: Unlock this item by defeating the Mom's Heart boss fight with Cain.
	Robo-Baby A familiar which follows the player and shoots lasers, similar to the Technology 1 item but with less damage. Robo-baby's laser does 3 damage and does not scale with damage stat upgrades. UNLOCK: Unlock this item by defeating the Mom's Heart boss fight with Judas.
	Little C.H.A.D A follower that drops half a red heart every 2 rooms. If you're fighting the C.H.A.D. boss and don't have Little Chad, you get it. UNLOCK: Unlock this item by defeating the C.H.A.D boss.
	The Book of Sin Spawns a random heart, key, coin, bomb, pill or Tarot card upon use. UNLOCK: Unlock this item by defeating all of the Seven Deadly Sins mini-bosses. Recharge Time: 4 Rooms.
	The Relic A blue cross follows the player and drops a Soul heart every 4 rooms. Can appear in the Angel Room item pool. UNLOCK: Unlock this item by defeating the Mom's Heart boss fight with Maggy.
	Little Gish A familiar which follows the player and shoots black tar tears, which slows enemy movement and projectile speed for a few seconds. If you're fighting Gish and don't have Little Gish, you get it. Little Gish's tears do 3.5 damage each and do not scale with damage. UNLOCK: Unlock this item by defeating the Gish boss.
	Little Steve A familiar which follows the player and shoots homing tears with the spoon bender effect. If you're fighting the Steven boss and don't have either Little Steve or the 'Steven' item, you have a 5/6 chance to get Little Steve. Little Steve's tears do 3.5 damage each and do not scale with damage stat upgrades. UNLOCK: Unlock this item by defeating the Steven boss.
	The Halo +1 Health Up. +0.3 Damage Stat. +0.2 Tears Stat. +2.75 Range Up (Base range = 23). +30% Player Movement Speed Up. This item does in fact give range up, contrary to what other sources claim. Can appear in the Angel Room item pool even before it is unlocked. UNLOCK: Unlock this item by defeating Mom's Heart with the Bible use item.
	Mom's Bottle of Pills Upon activation this item gives one of six random pills to the player. UNLOCK: Unlock this item by using several Blood Donation Machines. Recharge Time: 6 Rooms.
	The Common Cold Shots now have a 1/4 chance to poison enemies for a few seconds, dealing 2 damage per tick. The chance for the poison effect to activate stacks with other items which give tears a chance to apply poison to enemies. UNLOCK: Unlock this item by collecting any two of the following items in the same run: Roid Rage, The Virus, Growth Hormones.
	The Parasite Player's tears now split into two upon contact with anything. UNLOCK: Unlock this item by collecting two of the following items: Bob's Rotten Head, Dead Cat, Max's Head, Tammy's Head.
	The Dice Upon use, any 'pedestal' items will be re-rolled into another item that corresponds with that room's item pool. Pedestal items include items from the shop, devil deal room, angel room, boss room, treasure room or secret room. The Dice does not re-roll trinkets or other collectables which do not spawn on a 'pedestal'. Re-rolled items will pick from the item pool corresponding to the type of room it is in. This includes curse rooms which can re-roll items into Devil or God items. UNLOCK: Unlock this item by defeating the Mom's Heart boss fight with ???. Recharge Time: 3 Rooms.
	Mr. Mega +5 Bombs. All bombs dropped are now larger and do more damage (+50) and have a larger explosion. This item will increase damage of Dr. Fetus bombs. 14.3% chance to drop from the Super Wrath mini boss. UNLOCK: Unlock this item by destroying 10 tinted rocks.
	The Pinking Shears Cuts Isaac's head from his body for the current room.. The player can now fly for the current room and the decapitated body will attack for 7 damage per tick to any enemies in range. UNLOCK: Unlock this item by dying 100 times. Recharge Time: 6 Rooms.
	The Wafer Lowers all damage taken by half, rounding up to the nearest half-heart. This item becomes most effective in the Womb/Utero and any floor after it, where all damage taken is usually a whole heart if the player does not have The Wafer. UNLOCK: Unlock this item by defeating Mom's Heart for a seventh time.
	Money = Power Damage up depending on the number of coins the player currently has. Damage Modifier = coins * 0.04. At 99 coins, this item gives +3.96 Damage Stat. UNLOCK: Unlock this item by defeating Mom's Heart for an eighth time.
	Mom's Contacts Shots now have a random chance to freeze enemies solid for a few seconds. +2.75 Range Up (Base range = 23). UNLOCK: Unlock this item by picking up Mom's Eye and any of the following 'Mom' items: Mom's Heels, Mom's Lipstick, Mom's Pad, Mom's Bra.
	The Bean Upon activation, all enemies within close proximity take 5 damage and become poisoned for 3.5 damage per tick. Has an identical effect to the 'Bad Gas' Pill. UNLOCK: Unlock this item by destroying enough poops which are in random rooms. Recharge Time: 1 Rooms.
	Guardian Angel Gives the player an orbital angel which blocks shots and doubles the speed of all other orbitals (e.g. Pretty Fly or Cube of Meat). The Guardian Angel will also do 7 damage per tick if it comes into contact with any enemies. Can appear in the Angel Room item pool. UNLOCK: Unlock this item by killing Satan with Maggy.
	Demon Baby A familiar which follows the player and automatically fires tears at any enemies within range. The Demon Baby's tears do 3 damage each and do not scale with damage stat increases however the rate of tears is higher than usual. UNLOCK: Unlock this item by killing Satan with Eve.
	Mom's Knife The player replaces their ability to fire tears with a Knife which can be charged and released in a boomerang style. Base damage with Mom's Knife = 21 damage for charged shots and 7 damage for uncharged shots. The knife can do damage without even being charged, however charged shots do x3 damage compared to uncharged. The knife's damage does not appear to increase with increases to the range stat, as it was originally thought. Mom's knife over-rides Brimstone. UNLOCK: Unlock this item by killing Satan with the Isaac character.
	Ouija Board Gives the player spectral tears, which will travel through rocks or obstacles. This effect includes poop and fires, meaning it takes longer to extinguish or break them. An item commonly found in the Devil Room item pool.
	The 9 Volt Upon using a spacebar item, two bars of charge will automatically be re-charged. Upon pickup, the current spacebar item will be fully charged if it isn't already. Item found in the Shop Room item pool.
	Dead Bird One of Eve's starting item. When the player takes damage, the bird will start attacking nearby enemies for the current room, doing very frequent attacks at 2 damage each. UNLOCK: Unlock this item by making two deals with the devil in a single play through.
	Brimstone Standard tears are replaced with the ability to charge and fire a laser that penetrates anything in its path and does 300% damage. The laser can only be shot when fully charged unless you have the Chocolate Milk item. The Lump of Coal item will simply give +2 damage to this item. It is possible to charge the beam before entering the next room, meaning the first shot can be immediately released. There is a known glitch with Brimstone where if you spam the arrow key after releasing the laser, it can do significantly more damage. This glitch appears to make Brimstone hit the target between 3-5 times, as opposed to the normal 2 ticks. An item commonly found in the Devil Room item pool.
	Blood Bag +1 Health Up. +30% Player Movement Speed Up. Heals 5 whole red hearts. 1/30 chance to spawn from a broken Blood Donation Machine if you have not picked up the IV Bag before. Using Blood Donation Machines or picking up the Blood Bag does not increase the chance at a God/Angel/Devil Room to spawn, as it is sometimes believed.
	Odd Mushroom (Thin) Tear stat set to maximum. +1.7 Tears Stat. +30% Player Movement Speed Up. Damage down in an interesting way: 'damage = (damage * 0.9) - 0.4'.
	Odd Mushroom (Thick) +1 Health Up. +0.3 Damage Stat. +2.75 Range Up (Base range = 23). -10% Player Movement Speed Down. Increases the size of Isaac's head by 20%.
	Whore of Babylon When the player only has only half a heart of health left, Isaac enters a curse state which adds player speed and damage. +30% Player Movement Speed Up. +2.16 Damage Modifier if triggered by falling below 1 red heart. +1.5 Damage Modifier if triggered in a different room but the item is still enabled. One of Eve's starting items. UNLOCK: Unlock this item by making two deals with the devil in a single play through (which will also unlock the Eve character).
	Monster Manuel Spawns a random familiar for the current room only. Possible followers include: Brother Bobby, Cube of Meat (2nd or 3rd form), Halo of Flies, Distant Admiration, Sister Maggy, Lil Chubby, Robo-Baby, Little Gish, Little Steve, Guardian Angel, Demon Baby, Forever Alone. Cannot spawn a follower you already have. UNLOCK: Unlock this item by killing Satan with Judas. Recharge Time: 4 Rooms.
	Dead Sea Scrolls Upon use, uses a random activated item. The following item effects can occur: The Book of Belial, The Necronomicon, Mr. Boom!. Tammy's Head, Moms Bra, Kamikaze!, Mom's Pad, Bob's Rotten Head, Teleport!, Yum Heart, Lemon Mishap, Shoop Da Whoop!, Book of Shadows, Wiggle Worm, Anarchist Cookbook, The Hourglass, My Little Unicorn, Book of Revelations, The Nail, We Need To Go Deeper!, Deck of Cards, Monstro's Tooth, The Gamekid, The Book of Sin, Moms Bottle of Pills, The Pinking Shears. Recharge Time: 4 Rooms.
	Bobby - Bomb +5 Bombs All bombs now move towards the closest enemy. Bombs created by the Dr. Fetus item are also affected by this effect.
	Razor Blade Deals damage to the player in exchange for damage stat increases. Each use gives the player +1.2 damage per use for the current room. UNLOCK: Unlock this item by finishing the Womb with Eve. Recharge Time: Instant.
	Forget Me Now Upon activation, the current floor is refreshed with new rooms, monsters and items. UNLOCK: Unlock this item by killing Satan with ???. Recharge Time: One time use.
	Forever Alone Gives the player a blue attack fly that orbits from a long distance. The Forever Alone fly does 2 damage per tick and does not scale with damage stat changes. 14.3% chance to drop from the Super Envy mini boss. Killing the blueberry enemy last is just a placebo effect and does not give more chance for this item.
	Bucket of Lard +2 Health Up. -20% Player Movement Speed Down. 14.3% chance to drop from the Super Gluttony mini boss.
	A Pony Gives the player the ability to fly over environmental obstacles e.g. Rocks, gaps, spikes. The Pony isn't a static speed increase, it sets player speed to 150% of base speed or the player's current speed stat, depending on which is higher. The active use of this item allows the player to become invincible and charge across the screen, dealing 40 damage to anything it comes into contact with. There is a known bug with this item where if the player activates the pony and doesn't move, they become invincible until they move again. You can still fire tears while using this glitch using the mouse click. If you're fighting the Headless Horseman boss and don't have this item, you get it. Recharge Time: 4 Rooms.
	Bomb Bag A bag of bombs which follows the player and drops a random type of bomb every 3 rooms. Dropped bomb can either be a single Bomb, two bombs or a troll bomb. UNLOCK: Unlock this item by killing Satan with Cain.
	A Lump of Coal Damage up (and tear size) based on how long tears are in the air. +0.14 damage every frame on screen up to a maximum of 150 frames (5 seconds) for a total of +21 damage. If you have Brimstone or Technology, the Lump of Coal gives a flat +2 damage. This item synergises extremely well with range stat ups or the My Reflection item, since they both allow tears to maintain airtime for a longer period. Lump of Coal does nothing in terms of damage if you have Mom's Knife. This item is a 100% drop chance from the Krampus boss, who has a 10% chance of spawning in any Devil Deal Room. UNLOCK: Unlock this item by defeating the Krampus boss fight.
	Guppy's Paw Converts one heart container into 3 Soul hearts. 1/50 chance to spawn in a red chest. Counts as one item towards achieving Guppy state. Synergises well with the polaroid or other effects which activate when the player has less than one red heart. An item commonly found in the Devil Room item pool. Recharge Time: Instant.
	Guppy's Tail Upon clearing a room, the tail gives 1/3 chance to guarantee either a brown or gold chest with equal probability. If no chest spawns because of this item, there is a 1/3 chance that nothing will spawn after clearing the room. In other words, after clearing each room there is a 22% chance that any pickups drops will be negated (e.g. keys, bombs, coins etc.) An item commonly found in the Devil Room item pool. 1/25 chance to spawn in a red chest. 1/50 chance to spawn if you have not completed the '9 Deaths' challenge. Counts as one item towards achieving Guppy state. UNLOCK: Unlocks by completing the '9 Deaths' challenge.
	IV Bag Upon use, exchanges hearts for coins. 1/30 chance to spawn when using the Blood Donation Machine. The IV bag can be used multiple times per half heart of damage due to the length of invincibility after taking damage. Synergises very well with the Bloody Penny trinket. Can be extremely useful for the no-hit achievements since damage taken from the IV bag does not make you lose credit for the achievement. Recharge Time: Instant.
	Best Friend Places a 'decoy' Isaac on the floor which explodes for 110 damage to anything in range. This item is known to cause many glitches. If the best friend is activated and then gets hit by a blood laser or gets stomped, you will instantly die, no matter what health you are on. Recharge Time: 3 Rooms.
	Remote Detonator +5 Bombs. Bombs no longer explode after a set period of time and will only do so when you use this item. Recharge Time: Instant.
	Stigmata +1 Health Up. +0.3 Damage Stat.
	Mom's Purse Allows the player to hold one additional trinket. This item allows the player to pick up a second trinket when they have also picked up The Tick. Item found in the Shop Room item pool.
	Bob's Curse +5 Bombs All dropped bombs will explode for 60 damage (base bomb damage) and leaves a poison effect, which does 7 damage per tick. 14.3% chance to drop from the Super Sloth mini boss.
	Pageant Boy Spawns 7 coins around the player, which can be either pennies, nickels or dimes. Isaac wears a crown on his head when picked up.
	Scapular When the player gets down to half a heart left, they gain a Soul heart. This effect can only be used once per room. Getting this item with the Habit means you can get an infinite amount of rolls on your active item. If you also have the D6 you can infinitely roll item rooms until you get any item you want. Can appear in the Angel Room item pool.
	Spoon Bender +30% Player Movement Speed Up. +20% Shot Speed.
	Bum Friend A beggar who follows the player around and automatically picks up nearby coins. When picking up coins he will occasionally drop pickups (e.g. hearts, bombs, keys, pills, trinkets and tarot cards).
	Guppy's Head Upon activation, spawns 2-4 blue flies which damage nearby enemies. Blue flies do twice the player's damage. Counts as one item towards achieving Guppy state. 1/50 chance to spawn in a red chest. An item commonly found in the Devil Room item pool. Recharge Time: 1 Rooms.
	Prayer Card Gives the player half an eternal heart upon use. Can appear in the Angel Room item pool. Recharge Time: 6 Rooms.
	Notched Axe Breaks a single rock when activated. Recharge Time: 1 Rooms.
	Infestation When the player gets hit, 1-3 blue flies randomly spawn, which will attack enemies in close proximity. Blue flies do twice the player's damage.
	Ipecac Tears now become green projectiles which will arc over enemies and rocks and explode on contact, dealing 53.5 damage to anything in range at base damage. Damage increases will increase that number slightly. Tears down significantly: (delay = delay * 2.1 + 3). Since this item effectively gives you unlimited bomb, it is extremely useful for finding secret rooms and escaping from tricky rooms by bombing the door. Too many Range stat upgrades can make this item hard to control. Taking Ipecac and My Reflection is a terrible idea. Don't do it.
	Tough Love Isaac now randomly shoots teeth instead of tears which deal x3.2 more damage than normal shots. The probability to fire a tooth is linked to the player's Luck stat, with +10 luck being a guaranteed tooth and base luck giving you a 1/10 chance for each tear to be a tooth.
	The Mulligan On each successful hit, the player now has a 1/6 chance to spawn a blue fly which fies towards your current target and damages them. Blue flies do twice the player's damage.
	Technology 2 Fires a continuous laser with unlimited range in addition to normal tears, which also pierces all enemies. As Cain you will only fire the Tech 2 laser and no tears, due to his eyepatch. Damage down after calculations by a multiplier of 0.65. This -35% damage scales with all other damage increasing items. The laser damages every 3 frames (10 times per second).
	Mutant Spider Tears now shoot four at a time (Quad shot). Tears down significantly: (delay = delay * 2.1 + 3). This essentially lowers your tear rate by about 2 tears per second. The order in which you take Polyphemus and the Mutant Spider items does NOT matter, the combination will be the same no matter which item you took first.
	Chemical Peel Tears shot from Isaac's left eye now do +2 damage. Since Cain only fires from one eye, shots have a 50% chance to do +2 damage.
	The Peeper Gives the player an eye companion which floats around the room (similar to the eyes in the Peep boss fight) and damages enemies on contact. The Peeper does 8 damage per tick and does not scale with damage stat changes. Shots from the left eye are now coloured red but do no extra damage.
	The Habit With this item, when the player takes damage, 3 bars (half) of their space bar item are recharged. The Habit synergises extremely well with a few items: The Book of Revelations, the Nail and the Yum Heart can all technically make you invincible before the Womb and after the Womb if you acquire The Wafer.
	Bloody Lust Each time the player kills an enemy, damage up by +0.28 up to an upper cap of 2.3. The rage effect from this item can stack with the 'Samson's Lock' Trinket. Samson starts with this item. An item commonly found in the Devil Room item pool. UNLOCK: Unlock this item by completing the Womb with Samson.
	Crystal Ball Reveals the entire map and gives the player a random tarot card or soul heart. 1/30 chance to drop from a Fortune Machine. Recharge Time: 6 Rooms.
	Spirit of The Night Gives the player the ability to fly and spectral tears. An item commonly found in the Devil Room item pool.
	Crack the Sky Upon activation, this item creates beams of light at random locations in the current room, which deal damage to any enemies which come in contact with them. Each beam does 20 damage per tick, up to a maximum of 4 ticks per beam. The Conquest boss uses this item during the fight. Recharge Time: 4 Rooms.
	Ankh Upon death, the player respawns as the ??? with three Soul hearts. This is a one time use and all heart containers will be Soul hearts. This effect still works if the ??? is not available yet. Item found in the Secret Room item pool.
	Celtic Cross Upon taking damage, the player has a 1/5 chance to gain an invulnerability shield for 200 frames (6.66 seconds). UNLOCK: Unlock this item by completing the Cathedral floor with Maggy.
	Ghost Baby A familiar which follows the player and shoots spectral tears. Ghost Baby's tears do 3.5 damage each and do not scale with damage stat changes. If you take the Holy Water with this familiar, it will automatically turn it into Brother Bobby until you activate the Holy Water, at which point it will then turn back into Ghost Baby.
	The Candle A spacebar item which pushes a blue flame that damages anything in its path for significant damage (23 damage per tick). The blue flame destroys enemy projectiles, making it extremely useful during the Isaac and Blue Baby Boss fights. UNLOCK: Unlocks by completing the 'Dark was the Night' challenge. Item found in the Shop Room item pool. Recharge Time: 3-4 seconds.
	Cat-O-Nine-Tails +23% Shot Speed increase.
	The D20 Randomly re-rolls all pickups in the current room. This includes hearts, bombs, keys, coins, pills, tarot cards and trinkets. Synergises well with The Habit since it can be abused with the Blood Donation Machine. Also works on hostile bombs spawned by the War boss fight or XVI Tower tarot card. UNLOCK: Unlock this item by completing the Cathedral with Isaac. Recharge Time: 6 Rooms.
	Harlequin Baby A familiar which follows the player and shoots two tears diagonally. The Harlequin baby's tears do 4 damage each and do not scale with damage stat changes.
	Epic Fetus Tears now become guided missiles which do 80 damage each and are the same as the 'Doctor's Remote' item. Damage, tear and range stat upgrades do not affect this item. Epic Fetus over-rides every other item. Only found in the Secret Room item pool. UNLOCK: Unlocks by completing the 'Doctor's Revenge' challenge.
	Polyphemus Greatly increases the damage of Isaac's tears but lowers the tear stat to minimum. Tears down significantly: (delay = delay * 2.1 + 3). This essentially lowers your tear rate by about 2 tears per second. Damage up significantly: 'damage = 2 * (damage + 4)' assuming the player does not have The Inner Eye or Mutant Spider. If a tear kills an enemy with more damage than needed, the tear travels through it with the remaining damage. The order in which you take Polyphemus and the Mutant Spider items does NOT matter, the combination will be the same no matter which item you took first.
	Daddy Longlegs A shadow follows Isaac and stomps on enemies at random intervals. The Daddy Longlegs familiar does 20 damage per tick and usually hits twice per stomp, dealing a total of 40 damage. Damage stat upgrades do not increase this damage. The leg does not hurt Isaac. UNLOCK: Unlocks by completing the 'The Purist' challenge.
	Spider Butt Does 10 damage to all enemies in the room and slows down enemy speed and projectiles. Unlocks by completing the 'Spiderboy' challenge. UNLOCK: Unlocks by completing the 'Spiderboy' challenge. Recharge Time: 2 Rooms.
	Sacrificial Dagger Gives the player an orbital knife which does extremely high damage to anything it comes in contact with. The dagger does 15 damage per tick while it is in contact with something. Synergises well with high health runs or items which give you invulnerability. UNLOCK: Unlock this item by completing the Cathedral with Eve.
	Mitre An extra 50% chance that any non-specific heart spawns will become Soul hearts. Can appear in the Angel Room item pool.
	Rainbow Baby A familiar which follows the player and shoots a random tear effect every shot. Available effects include: Brother Bobby, Sister Maggy, Little Gish, Little Steve, Demon Baby, Ghost Baby and Harlequin Baby. UNLOCK: Unlock this item by completing the Cathedral with the Blue Baby character.
	Dad's Key Upon activation, all closed doors in the current room will be opened. This includes Challenge Rooms, the Devil Deal Room and standard rooms on the Chest floor. However, it does not always work with Angel and Devil Deal rooms. This does not work on rooms which normally need a key to open. Item found in the Secret Room item pool. UNLOCK: Unlocks by completing the Chest with any character. Recharge Time: 2 Rooms.
	Stem Cells +1 Health Up. +16% Shot Speed Increase.
	Portable Slot Does exactly what it says on the tin - Using the portable slot gives you the same effect as the Red Slot machine. Using this in a boss room to spawn a black fly after defeating the boss will enable the player to leave the room and re-enter, which will refresh the boss room and therefore give you another item. Recharge Time: Instant.
	Holy Water When the player takes damage, the bottle breaks and leaves a pool on the floor which deals 8 damage (per tick) to enemies which walk into it, exactly like the Lemon Mishap effect. This item has a known bug where most followers will be downgraded into Brother Bobby.
	Fate The player gains the ability to fly and is given an eternal heart. This item only has a 50% chance to be in the Golden Chest item pool.
	The Black Bean Upon taking damage, all enemies in close proximity will be affected by 5 poison damage and then a poison effect of 3.5 damage per tick. The effect is exactly the same as 'The Bean' item.
	White Pony Allows Isaac to fly while this item is held. Has a spacebar effect which is the same as the Crack the Sky item effect. Sets player speed to 150% of base speed, unless current speed stat is higher. If you're fighting the Conquest Boss and don't have White Pony, you get it. Recharge Time: 6 Rooms.
	Sacred Heart Tears are now much larger and slower but move towards enemies with a homing effect. Damage up significantly: damage = (damage * 2.3) + 1. -0.4 Tear Stat Modifier. -25% Shot Speed Decrease. +4.125 Range Up (Base range = 23). Fully heals all current red heart containers. +1 Soul heart. Can appear in the Angel Room item pool.
	Tooth Picks +16% Shot Speed Increase. This item is falsely labelled as Tear Stat Up.
	Holy Grail Gives the player the ability to fly. +1 Health Up. Can appear in the Angel Room item pool.
	Dead Dove Gives the player flying and spectral tears. This is the Angel Room equivalent of the 'Spirit of the Night' item. Can appear in the Angel Room item pool.
	Blood Rights Upon activation, this item takes one red heart and damages all enemies in the room for 40 damage. If you spam press this item, the first use will take a whole heart but each subsequent use takes only half a heart for as long as you spam spacebar. UNLOCK: Unlock this item by completing Sheol as Samson. Recharge Time: Instant.
	Guppy's Hairball Follows behind Isaac and can be swung around to deal damage on contact to enemies equal to: (3 + size 2). The hairball size starts at 1 and has a random chance to become larger each time it kills an enemy (up to a maximum of size = 6), with a probability of 1/x, where X is the current size of the hairball. At size one, the chance is 1/1; at size two, the chance is 1/2 etc. The size of the hairball persists between rooms, but at the end of each floor it decreases in size by roughly half. The exact calculation is "size = floor(size * 0.5 + 0.5)" This item does not count towards achieving Guppy state. UNLOCK: Unlocks by taking 3 of the 4 Guppy items and transforming into Guppy the Cat.
	Abel A familiar which follows the player and mirrors the player's movements and shoots in the opposite direction. Abel's tears do 3.5 damage each and do not scale with damage stat changes. UNLOCK: Unlock this item by completing the Cathedral with Cain.
	SMB Super Fan +1 Health Up. +0.3 Damage Stat. +0.2 Tears Stat. -20% Player Movement Speed Down. UNLOCK: Unlocks by completing the 'MEAT 4 EVAR' challenge.
	Pyro +99 bombs. Has a 50% chance to be in the Secret room item pool.
	3 Dollar Bill Gives a random tear effect in each room. Tear effects include: The Sad Onion, The Inner Eye, Spoon Bender, My Reflection, Number One, Lucky Foot, Magneto, Mom's Contact, Ouija Board, Speed Ball, Tough Love. Since it gives the magneto effect, you can repeatedly leave and re-enter a room to obtain pick-ups which you could not normally get.
	Telepathy for Dummies Gives the Spoon Bender (homing shots) effect for the current room. Recharge Time: 2 Rooms.
	MEAT! +1 Health Up. +0.3 Damage Stat. This item is falsely marked as a Tears Stat Up on the in-game description.
	Magic 8 Ball +16% Shot Speed Increase. Drops one random Tarot card. This item is falsely marked as a Tears Stat Up on the in-game description.
	Mom's Coin Purse Spawns four random pills around the player.
	Squeezy Spawns 2 Soul hearts. +0.4 Tears Stat.
	Jesus Juice +0.5 Damage Stat. +2.75 Range up (Base range = 23). This item is falsely marked as a Tears Up on the in-game description.
	Box Spawns one of each pick-up. Pickups: 1 heart, 1 key, 1 bomb, 1 coin, 1 card, 1 pill, 1 trinket and can spawn variations of each. This item does not decrease your player movement speed which is sometimes believed.

Cards:
	X - Wheel of Fortune Spawns a Slot Machine or a Fortune Machine. If you spawn a slot machine in the super-secret room that has an eternal heart in it, all hearts that spawn from the slot machine will be eternal hearts. If the card is used in the Boss room after you beat it and you manage to spawn a blаck fly with the slot machine, this can be used to refresh the Boss room by leaving a re-entering the room.
	XV - The Devil Gives the Book of Belial effect for the current room, which is +2 Damage. Adds a x1.5 damage multiplier ONLY if the player also has 'Blood of the Martyr'.
	XIII - Death Does 60 damage to all enemies in the room.
	XI - Strength Gives the player the Magic Mushroom effect, which increases all stats by 1 except for tears.
	O - The Fool Teleports the player to the starting room of the current floor. Has a limited number of uses, however it can allow you to teleport out of curse rooms, challenge rooms and the Mom's Foot boss fight.
	I - The Magician For the current room, tears now have the Spoon Bender effect, which allows them to curve towards enemies and gives them a purрle appearance.
	IX - The Hermit Teleports the player to the Shop. On or below the Womb, this acts as a random teleport, since there are no shops on those floors.
	XVIII - The Moon Telepots the player to the Secret Room.
	XII - The Hanged Man Gives the player the flying effect for the current room, allowing the player to fly over obstacles in the room. This card is useless if you have any item which allows you to permanently fly.
	XX - Judgement Spawns a beggar. Any beggar spawned has a 33% chance to become a devil beggar. Normal beggars are guaranteed to drop something after 8 coins. Devil beggars have a 1/4 chance to drop something (1/3 if you have the lucky foot). The beggar will pay out items related to the current room (or health increasing items), which can be used to exploit the game in a number of ways. Angel Rooms, Devil Deal Rooms and Curse rooms will drop items from their relevant item pools.
	VII - The Chariot Grants the same effect as 'My Little Unicorn', which is 180 frames (6 seconds) of invincibility and causes damage to enemies on contact.1 +28% Player Movement Speed Up for the duration.
	VI - The Lovers Spawns 2 red hearts on the floor.
	XXI - The World Reveals the entire map and shows the icons for every room which has one. This is completely useless if you currently have both the Treasure Map and The Compass.
	VIII - Justice Spawns 1 bomb, 1 key, 1 coin, 1 heart, which can be random variants of each.
	XIV - Temperance Spawns a Blood Donation Machine.
	IV - The Emperor Teleports the player to the Boss room on the current floor. If used on an XL floor, it will take you to the first of the two boss fights. If used after you defeat the Mom's Foot boss fight, it allows you to exit the room again.
	XVI - The Tower Spawns six troll bombs at random locations in the current room.
	V - The Hierophant Spawns 2 Soul hearts on the floor.
	II - The High Priestess Summons Mom's foot which will stomp on a random enemy in the current room, dealing massive damage. If no enemies are in the current room, the foot will target Isaac (and do damage if it hits), however it can be used to break rocks or open secret rooms. There is a known glitch with this card where if you pause the game at the perfect moment when the foot comes down, the shadow will stay on screen and stomp for a second time. This can loop infinitely as long as you can pause the game at the exact moment. Very hard to achieve.
	III - The Empress Gives the player the Whore of Babylon effect with higher damage (3.375 base damage increase) and +30% Player Movement Speed Up for the current room.
	XIX - The Sun A card with three uses: A full heal, damages all enemies in the current room for 100 damage and reveals the entire map for the current floor (Treasure Map + The Compass).
	XVII - The Stars Teleports the player to the Item Room. On or below the Womb, this acts as a random teleport, since there are no item rooms on those floors.
	2 of Spades Doubles the number of keys you have. If you have no keys, it gives you two.
	2 of Clubs Doubles the number of Bombs you have. If you have no bombs, it gives you two.
	2 of Hearts Doubles your current red hearts up to full health. If you have half a heart left, the card recovers your first two heart containers. This card is useless for the Blue Baby.
	2 of Diamonds Doubles the number of coins you have. If you have no coins, it gives you two.
	The Joker Teleports you to the Devil Deal Room on the current floor. The Devil Room can be replaced by an Angel Room or even contain the Krampus boss fight. In the Womb/Utero 2, the devil room will still contain a trap door down to Sheol when accessed via use of this card.

Trinkets:
	Fish Head Every time you get hit, you spawn one blue fly. Blue flies do twice the player's damage. UNLOCK: Unlocks by completing the 'Lord of the Flies' challenge.
	Pinky Eye /10 chance to make a poison tear which also does 4 poison damage per tick. The chance for the poison effect to activate stacks with other items which give tears a chance to apply poison to enemies.
	Push Pin 1/10 chance to make a spectral and piercing tear.
	Liberty Cap 1/4 chance to give one of the Mushroom item effects or the Compass effect Effects include: Compass, Mini Mush, Odd Mushroom (thin), Odd Mushroom (thick). You can force the game to temporarily give you the Compass effect by repeatedly going back and forth through the same door, so that you can see where all the rooms with map icons are located. It is not possible to farm infinite soul hearts if you have Guppy's Paw and walk between rooms until you get the Odd Thick Mushroom effect.
	Umbilical Cord If you take damage which leaves you on one half heart left, you gain Little Steve for the remainder of the room. This effect does take Soul hearts into account, unlike the effects of other items such as The Polaroid of Whore of Babylon.
	Child's Heart An additional 1/10 chance to give you a heart at the end of a room. An additional 2/3 chance to give you a heart while opening a chest.
	Curved Horn +2 Damage Up. This damage is added to total Effective Damage after calculations and character damage modifiers, therefore it is a static +2 damage (Except when applied with either Sacred Heart or Technology 2). UNLOCK: Unlock this item by completing the Cathedral with Judas.
	Rusted Key An additional 1/10 chance to give you a key OR a golden chest at the end of a room, with equal chance. An additional 2/3 chance to give you a key while opening a chest.
	Goat Hoof +15% Player Movement Speed Up. This speed increase can go over the speed cap of 200%.
	Mom's Pearl An extra 10% chance that any non-specific heart drops will become a Soul heart. This does stack with the Mitre effect.
	Cancer Tear delay decreased by 2. This increases tear rate by different amounts based on your current tears stat. At a delay of 24 (e.g. Polyphemus), this trinket adds 25% more tear rate. At max fire rate this adds 200% more tear rate, therefore is more useful as you gain more Tears Stat. This trinket can break the tear rate of fire cap. This trinket does not reduce the drop chance of hearts of any kind, which is often believed to be true.
	Red Patch 1/5 chance when taking damage to get +3 'razor' points. +1.8 damage up every time the effect activates. Damage up calculation with regards to razor points: 'damage = damage + (razor points * 0.6)'
	Match Stick An additional 1/10 chance to give you a bomb at the end of a room. An additional 2/3 chance to give you a bomb while opening a chest.
	Lucky Toe Increases chance to drop an item at the end of the room by ~10%. If you also have the lucky foot, this item only increases drop chance by 2%. NLOCK: Unlocks by completing the '7 Years Bad Luck' challenge.
	Cursed Skull When you are hit with 1/2 a red heart remaining, you are teleported to the previous room. This does not count Soul hearts and therefore this item will teleport the ??? character every hit.
	Safety Cap An additional 1/10 chance to give you a pill at the end of a room. An additional 2/3 chance to give you a pill while opening a chest.
	Ace of Spades An additional 1/10 chance to give you a tarot card at the end of a room. An additional 2/3 chance to give you a tarot card while opening a chest.
	Isaac's Fork 1/10 chance to heal half a heart after clearing a room.2
	The Polaroid Grants access to the Chest floor if equipped while fighting the Isaac boss fight. Grants 150 frames (5 seconds) of invincibility when you are hit with 1/2 heart remaining. This effect does not count Soul hearts and will give invulnerability every time the player gets hit if they only have Soul hearts or is playing as ???. 100% drop chance from the Mom's Foot boss fight. If you manage to empty the Trinket Pool (i.e. see them all drop) before getting to the Mom's Foot boss fight, The Polaroid will not drop here. UNLOCK: Unlock this item by completing the Cathedral 6 times.
	A Missing Page 1/20 chance to deal 40 damage to all enemies in the room when the player takes damage. Gives the player a second free hit on the Blood Donation Machine if the effect procs.
	Bloody Penny 50% chance to gain a half heart when picking up any type of coin. Synergises very well with Blood Donation machines or the IV bag, often allowing the player to refill their hearts and max out on coins. UNLOCK: Unlock this item by completing the Cathedral as Samson.
	Burnt Penny 50% chance to gain a bomb when picking up any type of coin. UNLOCK: Unlocks by completing the 'Large Marge' challenge.
	Flat Penny 50% chance to gain a key when picking up any type of coin.
	Counterfeit Penny 50% chance to give +1 coin when picking up any type of coin, which is automatically added to the total. This can only drop from breaking a Golden Poop with 1/3 chance and is not in the normal Trinket pool. UNLOCK: Unlocks by completing the 'Isaac was good today' challenge.
	The Tick This trinket cannot be replaced when you pick it up, meaning you are unable to go to the Chest floor unless you also have the Mom's Purse effect. When you enter a boss room, The Tick recovers 1 heart. Immediately removes 15% of an enemy's health if it has over 60hp (All bosses have over 60hp).
	Isaac's Head While held, gives the player a familiar which follows the player and shoots piercing tears. Isaac's Head's tears do 3.5 damage each and do not scale with damage stat changes. UNLOCK: Unlock this item by completing the Chest as Isaac.
	Maggy's Faith Grants the player an eternal heart at the beginning of every floor. This effect works if you refresh the floor with the Forget Me Now item. UNLOCK: Unlock this item by completing the Chest as Maggy.
	Judas' Tongue Items which cost 2 heart containers in a deal with the Devil will be reduced to 1 heart instead. All 1 heart deals and 3 Soul heart deals are not reduced. UNLOCK: Unlock this item by completing the Chest as Judas. However this will grant you the achievement "Cains Eye".
	???'s Soul Creates a familiar which moves around the room in a similar fashion to The Peeper. Other familiars the player currently has may follow ???'s soul instead of the player. ???'s Soul's tears do 3.5 damage each and do not scale with damage stat changes. UNLOCK: Unlock this item by completing the Chest as Eve. However this will grant you the achievement "Judas' Tongue".
	Samson's Lock When you kill an enemy, you have a 1/15 chance to get +0.5 damage up (up to a cap of 3.3). Similar effect to the Bloody Lust item, however the rage effect is not guaranteed with Samson's Lock. The rage effect from this trinket does stack with the 'Bloody Lust' item. UNLOCK: Unlock this item by completing the Chest as Samson. However this will grant you the achievement "Eves Bird Foot".
	Cain's Eye Gives a 25% chance to reveal the entire map at the start of a new floor. UNLOCK: Unlock this item by completing the Chest as Cain. However this will grant you the achievement "???s Soul".
	Eve's Bird Foot Gives a 1/20 chance when you kill something to spawn the Dead Bird familiar for the current room. UNLOCK: Unlock this item by completing the Chest as ???. However this will grant you the achievement "Samsons Lock".
	The Left Hand Replaces chests with Red Chests. This also affects Golden chests UNLOCK: Unlocks by defeating the Ultra Pride mini-boss fight.

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